May 20, 2014

Newer antidepressants and pediatric pulmonary hypertension

Query 12-10: Newer antidepressants and Persistent Pulmonary Hypertension of the Newborn (PPHN)

This project was funded (by CIHR-DSEN, as a query posed by Health Canada) on November 2013 for one year (Nominated PI A. Berard, co-PI S. Bernatsky, co-investigator M. Abrahamowicz).

In our analyses, we used data from three pre-established pregnancy cohorts (Quebec, Saskatchewan and US Medicaid). At present, all three cohorts have been built using a similar protocol and all variables have been defined (exposure, outcome and covariates/confounders).

Results were discussed at the June 2015 Reseau Quebecois de Recherche sur les Medicaments (RQRM) meeting and the International Society for Pharmacoepidemiology (ICPE) meeting in August 2015.

Our manuscript has been published:

Berard A, Sheehy O, Zhao JP,Vinet E, Bernatsky S, Abrahamowicz M. SSRI and SNRI use during pregnancy and the risk of persistent pulmonary hypertension of the newborn. Br J Clin Pharmacol. 2017 May;83(5):1126-1133.

For more information contact: Jessica (Lifang) Wang. Research Coordinator. [email protected]   514.934.1934 ext.44718