This section includes research papers, white/grey papers and published books.

• Real‑world analyses of therapy discontinuation of checkpoint inhibitors in metastatic melanoma patients (1905 downloads )
• Effectiveness and safety of tofacitinib in rheumatoid arthritis: a cohort study (2096 downloads )
• Protocol for a scoping review of post-trial extensions of randomised controlled trials using individually linked administrative and registry data (2190 downloads )
• Network meta-analysis incorporating randomized controlled trials and nonrandomized comparative cohort studies for assessing the safety and effectiveness of medical treatments: challenges and opportunities (2111 downloads )
• Risk of acute myocardial infarction with real‐world NSAIDs depends on dose and timing of exposure (2135 downloads )
• Using multiple pharmacovigilance models improves the timeliness of signal detection in simulated prospective surveillance (2164 downloads )
• Competing risks modelling of cumulative effects of time-varying drug exposures (2095 downloads )
• Adjustment for time-dependent unmeasured confounders in marginal structural Cox models using validation sample data (2127 downloads )
• Breaking the nested case-control data offered several advantages for risk estimation (2083 downloads )
• Martingale residual-based method to control for confounders measured only in a validation sample in time-to-event analysis (2051 downloads )
• Correcting for measurement error in time-varying covariates in marginal structural models (2110 downloads )
• The missing cause approach to unmeasured confounding in pharmacoepidemiology (2024 downloads )
• Conditions for confounding of interaction (2102 downloads )
• The proportion of all previous patients was a potential instrument for patients' actual prescriptions of nonsteroidal anti-inflammatory drugs (2052 downloads )
• The impact of exposure model misspecification on signal detection in prospective pharmacovigilance (2102 downloads )
• Flexible Marginal Structural Models for Estimating the Cumulative Effect of a Time-Dependent Treatment on the Hazard: Reassessing the Cardiovascular Risks of Didanosine Treatment in the Swiss HIV Cohort Study (2030 downloads )
• Comparison of Approaches to Weight Truncation for Marginal Structural Cox Models (2131 downloads )
• Comparison of alternative models for linking drug exposure with adverse effects (2115 downloads )
• Application of pharmacogenomics to investigate adverse drug reactions to the disease-modifying treatments for multiple sclerosis: a case–control study protocol for dimethyl fumarate-induced lymphopenia (2003 downloads )
• Common variation near IRF6 is associated with IFN-β-induced liver injury in multiple sclerosis (1933 downloads )
• Treatment Strategies in Early Rheumatoid Arthritis Methotrexate Management: Results From a Prospective Cohort (1968 downloads )
• Direct-Acting Antivirals for Hepatitis C: Predictors of Early Discontinuation in the Real World (2193 downloads )
• Multiple sclerosis drugs: how much bang for the buck? (3236 downloads )
• Effectiveness and cost-effectiveness of interferon beta and glatiramer acetate in the UK Multiple Sclerosis Risk Sharing Scheme at 6 years: a clinical cohort study with natural history comparator (3442 downloads )
• Determinants of non-adherence to disease-modifying therapies in multiple sclerosis: a cross-Canada prospective study (3424 downloads )
• Adherence and persistence to drug therapies for multiple sclerosis: a population-based study (4013 downloads )
• Association between selective serotonin reuptake inhibitors use and multiple sclerosis disability progression (3432 downloads )
• Modelling disease progression in relapsing-remitting onset multiple sclerosis using multilevel models applied to longitudinal data from two natural history cohorts and one treated cohort (3456 downloads )
• On the application of statistical learning approaches to construct inverse probability weights in marginal structural Cox models: hedging against weight-model misspecification (2424 downloads )
• Comparison of statistical approaches dealing with time-dependent confounding in drug effectiveness studies (2641 downloads )
• Adherence to disease modifying therapies for multiple sclerosis and subsequent hospitalizations (2629 downloads )
• Disease-modifying drugs for multiple sclerosis and infection risk: a cohort study (2381 downloads )
• Evaluating the safety of beta-interferons in MS: a series of nested case- control studies (2308 downloads )
• Assessing the long-term effectiveness of interferon-beta and glatiramer acetate in multiple sclerosis: final ten year results from the UK multiple sclerosis risk sharing scheme (2878 downloads )
• Multiple sclerosis: effect of beta interferon treatment on survival (2435 downloads )
• Comparative effectiveness and safety of biosimilar and legacy drugs (2494 downloads )
• Alternative design and analytical techniques for longitudinal rheumatology studies: improved understanding of outcomes (4283 downloads )
• Trends in population-based incidence and prevalence of juvenile idiopathic arthritis in Manitoba, Canada (3606 downloads )
• Validation of administrative case ascertainment algorithms for chronic childhood arthritis in Manitoba, Canada (2796 downloads )
• SMART thinking: a review of recent developments in sequential multiple assignment randomized trials (2582 downloads )
• Breaking the matching in nested case-control data offered several advantages for risk estimation (2814 downloads )
• Early medication use in new-onset rheumatoid arthritis may delay joint replacement: results of a large population-based study. (2783 downloads )
• The longterm effect of early intensive treatment of seniors with rheumatoid arthritis: a comparison of 2 population-based cohort studies on time to joint replacement surgery (2486 downloads )
• Launch of a checklist for reporting longitudinal observational drug studies in rheumatology: a EULAR extension of STROBE guidelines based on experience from biologics registries (2708 downloads )
• Diagnostic accuracy of algorithms to identify hepatitis C status, AIDS status, alcohol consumption and illicit drug use among patients living with HIV in an administrative healthcare database (3859 downloads )
• The economic impact of clostridium difficile infection: a systematic review (3455 downloads )
• The use of administrative health care databases to identify patients with rheumatoid arthritis (2915 downloads )
• Long-term cost-effectiveness of transcatheter versus surgical closure of secundum atrial septal defect in adults (3702 downloads )
• Specialized adult congenital heart disease care: the impact of policy on mortality (3956 downloads )
• Distribution and drivers of costs in type 2 diabetes mellitus treated with oral hypoglycemic agents: A retrospective claims data analysis (4084 downloads )
• Comparison of survival and hospitalization rates between Medicare patients with advanced NSCLC treated with bevacizumab–carboplatin–paclitaxel and carboplatin–paclitaxel: a retrospective cohort study (3908 downloads )
• Impact of low-grade adverse events on health-related quality of life in adult patients receiving imatinib or nilotinib for newly diagnosed Philadelphia chromosome positive chronic myelogenous leukemia in chronic phase (3832 downloads )
• Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010 (3532 downloads )
• Psoriasis and risk of diabetes-associated microvascular and macrovascular complications (3539 downloads )
• Clinicians' perspectives on patient satisfaction in adult congenital heart disease clinics: a dimension of health care quality whose time has come (3810 downloads )
• A difference-in-differences approach to estimate the effect of income-supplementation on food insecurity (3747 downloads )
• Early medication use in new-onset rheumatoid arthritis may delay joint replacement: results of a large population-based study (2266 downloads )
• Rheumatoid arthritis prevalence in Quebec (3037 downloads )
• Disease risk score (DRS) as a confounder summary method: systematic review and recommendations (2946 downloads )
• Osteoporosis management among chronic glucocorticoid users: a systematic review (3697 downloads )
• Adherence to osteoporosis pharmacotherapy is underestimated using days supply values in electronic pharmacy claims data (2972 downloads )
• Osteoporosis management and fractures in the Métis of Ontario, Canada (3028 downloads )
• Interrupted time series analysis in drug utilization research is increasing: systematic review and recommendations (3426 downloads )
• Examining exposure misclassification of oral bisphosphonate therapy and the associated fracture risk: a cohort study (3071 downloads )
• The influence of time-dependent drug exposures on joint surgeries in rheumatoid arthritis patients (5596 downloads )
• The influence of drug exposures and comorbidity on survival in patients with rheumatoid arthritis (2306 downloads )
• Administrative healthcare data: a guide to its origin, content and application using SAS (6315 downloads )