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Developing novel methods to study drug safety and effectiveness
514.934.1934 ext.44844
McGill University Health Centre

Author Archive

24
Jan

Join the DSECT/DSEN Monthly Seminar Series!   DSECT/DSEN present monthly online seminars for faculty, staff, trainees, decision makers and other stakeholders engaged in the field of drug safety and effectiveness.   The Drug Safety and Effectiveness Cross-Disciplinary Training (DSECT) Program “bridges biosciences, clinical therapeutics, population health, epidemiology, biostatistics, and health services and policy research to better understand […]

09
Aug

Q# 16-08: Ondansetron and Fetal Abnormality   This project aims to investigate the association between use of ondansetron in pregnancy and the risk of fetal abnormalities. We identified 50,269 pregnancies with antiemetic medications exposure during pregnancy:  54 pregnancies exposed to ondansetron, 49,885 pregnancies exposed to pyridoxine/doxylamine, and 1,735 pregnancies exposed to metoclopramide. Results indicated increased […]

09
Aug

Query# 16-07: Options for appropriate prescribing   This project aims to conduct a review of interventions to support appropriate prescribing of opioid. Previously, a full report was submitted to DSEN describing the results from the systematic review and an abstract with a summary of the review was presented at the 33rd International Conference on Pharmacoepidemiology […]

09
Aug

Query# 16-01: Use of social media and crowd sourcing data analytics to increase drug safety and public awareness   The objective of this study is to assess the value of using social media surveillance for pharmacovigilance in Canada. The platform installation and training has been completed and the protocol is being developed for the evaluation […]

11
Aug

Query 16-03: Preventable adverse drug reactions (ADR) as percentage of total ADRs   This project was funded in June 2016 for two years. The query will be addressed in two phases: i) in phase I, we will conduct a retrospective chart review of patients diagnosed with an ADE to determine the preventability of the event, […]

11
Aug

Query 15-11: Intravitreal bevacizumab for retinal conditions: real-world safety assessment   This project was originated with a query by CADTH and funded in June 2016 for one year. The objective of this study is to examine ocular complications of anti-VEGF injections given for neovascular age-related macular degeneration (AMD) and other retinal conditions in population-based cohorts.   […]

11
Aug

Query 11-03: How do thiazide diuretics compare to ACE inhibitors and combination antihypertensive products in terms of effectiveness (and cost-effectiveness) for the management of hypertension in non-diabetic patients?   This project, which originated with a query by British Columbia Ministry of Health, was funded in 2013 for 3 years. Initial results have been generated and discussed […]

26
May

Drs. Sasha Bernatsky and Louise Pilote received funding from the Drug Safety and Effectiveness Network (DSEN) Rapid Funding for DSEN Targeted Research to continue developing novel methods using prospective longitudinal cohorts and responding to key knowledge gaps regarding drug safety and effectiveness through the Enhanced Cohort project.   Research Project Title: Canadian Early Arthritis Cohort […]

25
Jun

Stay tuned for a DSEN/DSECT webinar collaboration! The Drug Safety and Effectiveness Cross-Disciplinary Training (DSECT) Program “bridges biosciences, clinical therapeutics, population health, epidemiology, biostatistics, and health services and policy research to better understand choosing, using and losing medications within the context of medication safety and effectiveness.” DSECT/DSEN presents “monthly online seminars for faculty, staff, trainees, decision makers and […]

20
May

Query 11-04: How does real world use of insulin glargine compare to NPH insulin in terms of effectiveness and safety (and ideally cost-effectiveness) for the management of type 1 diabetes mellitus? What is the comparative effectiveness and safety of sitagliptan and NPH insulin for the management of type 2 diabetes (T2D) not controlled by metformin […]

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